| Symbol | Company | Weighting |
|---|---|---|
| CRNX | CRINETICS PHARMACEUTICALS INC | 3.56% |
| APGE | APOGEE THERAPEUTICS INC | 2.53% |
| PSNL | PERSONALIS | 2.48% |
| IMVT | IMMUNOVANT INC | 2.23% |
| ICLR | ICON PLC | 2.16% |
| ARQT | ARCUTIS BIOTHERAPEUTICS | 2.08% |
| WGS | GENEDX HLDGS CORP NPV | 2.08% |
| ACHC | ACADIA HEALTHCARE CO INC | 2.06% |
| EWTX | EDGEWISE THERAPEUTICS | 1.93% |
| DNLI | DENALI THERAPEUTICS INC. | 1.89% |
| PVLA | PALVELLA THERAPEUTICS, INC. | 1.88% |
| RVMD | REVOLUTION MEDICINES INC | 1.87% |
| RCUS | ARCUS BIOSCIENCES INC | 1.86% |
| HIMS | HIMS & HERS HEALTH, INC. | 1.86% |
| HUM | HUMANA INC | 1.83% |
| LLY | ELI LILLY CORP | 1.83% |
| THC | TENET HEALTHCARE CORP | 1.83% |
| RGEN | REPLIGEN CORP | 1.79% |
| DGX | QUEST DIAGNOSTICS | 1.79% |
| WAT | WATERS CORP | 1.76% |
| ABBV | ABBVIE INC | 1.75% |
| ARWR | ARROWHEAD PHARMACEUTICALS INC | 1.75% |
| KRYS | KRYSTAL BIOTECH INC | 1.73% |
| ABT | ABBOTT LABORATORIES | 1.72% |
| MRK | MERCK & CO. NEW | 1.71% |
| MCK | MCKESSON CORP | 1.71% |
| LH | LABCORP HOLDINGS INC | 1.70% |
| DHR | DANAHER CORP | 1.70% |
| CVS | CVS HEALTH CORPORATION | 1.69% |
| AVTX | AVALO THERAPEUTICS INC | 1.68% |
| PCVX | VAXCYTE INC | 1.66% |
| SGMT | SAGIMET BIOSCIENCES INC | 1.61% |
| SNDX | SYNDAX PHARMACEUTICALS, INC. | 1.59% |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 1.59% |
| ASND | ASCENDIS PHARMA A/S DKK 1.0 ADR | 1.59% |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 1.58% |
| TSHA | TAYSHA GENE THERAPIES I | 1.58% |
| DXCM | DEXCOM INC | 1.57% |
| MDT | MEDTRONIC PLC | 1.57% |
| SYK | STRYKER CORP | 1.55% |
| BDX | BECTON DICKINSON & CO | 1.55% |
| PODD | INSULET CORP | 1.54% |
| EYPT | EYEPOINT INC | 1.54% |
| NVS | NOVARTIS AG-ADR | 1.53% |
| PRAX | PRAXIS PRECISION MEDICINES, INC. | 1.53% |
| MLYS | MINERALYS THERAPEUTICS I | 1.53% |
| UNH | UNITEDHEALTH GROUP INC | 1.52% |
| GEHC | GE HEALTHCARE TECHNOLOGIES INC | 1.46% |
| INSM | INSMED INC | 1.45% |
| ZTS | ZOETIS INC | 1.42% |
| IDXX | IDEXX LABS CORP | 1.41% |
| UTHR | UNITED THERAPEUTICS CORPS | 1.37% |
| HTFL | HEARTFLOW INC | 1.35% |
| AZN | ASTRAZENECA PLC | 1.33% |
| SPRY | ARS PHARMACEUTICALS | 1.23% |
| BSX | BOSTON SCIENTIFIC | 1.16% |
| IONS | IONIS PHARMACEUTICALS INC | 1.13% |
| ISRG | INTUITIVE SURGICAL INC | 1.05% |
| OCS | OCULIS HOLDING AG | 0.59% |
Read a prospectus and summary prospectus (if available) carefully before investing. It contains the investment objective, risks charges, expenses and the other information, which should be considered carefully before investing. To obtain a prospectus and summary prospectus (if available) <a href="/services/prospectuses-and-reports">click here</a> or call 800.820.0888.
Investing involves risk, including the possible loss of principal.
Guggenheim Investments represents the following affiliated investment management businesses of Guggenheim Partners, LLC: Guggenheim Partners Investment Management, LLC, Security Investors, LLC, Guggenheim Funds Distributors, LLC, Guggenheim Funds Investment Advisors, LLC, Guggenheim Corporate Funding, LLC, Guggenheim Wealth Solutions, LLC, Guggenheim Private Investments, LLC, Guggenheim Investments Loan Advisors, LLC, Guggenheim Partners Europe Limited, Guggenheim Partners Japan Limited, and GS GAMMA Advisors, LLC. Securities offered through Guggenheim Funds Distributors, LLC.
© 2026 Guggenheim Investments. All Rights Reserved.
Research our firm with FINRA Broker Check.
Not FDIC Insured • No Bank Guarantee • May Lose Value
This website is directed to and intended for use by citizens or residents of the United States of America only. The material provided on this website is not intended as a recommendation or as investment advice of any kind, including in connection with rollovers, transfers, and distributions. Such material is not provided in a fiduciary capacity, may not be relied upon for or in connection with the making of investment decisions, and does not constitute a solicitation of an offer to buy or sell securities. All content has been provided for informational or educational purposes only and is not intended to be and should not be construed as legal or tax advice and/or a legal opinion. Always consult a financial, tax and/or legal professional regarding your specific situation. Investing involves risk, including the possible loss of principal.
