| Symbol | Company | Weighting |
|---|---|---|
| RVMD | REVOLUTION MEDICINES INC | 4.73% |
| KRRO | KORRO BIO | 3.60% |
| ARWR | ARROWHEAD PHARMACEUTICALS INC | 3.18% |
| EWTX | EDGEWISE THERAPEUTICS | 3.09% |
| TVTX | TRAVERE THERAPEUTICS INC | 3.04% |
| URGN | UROGEN PHARMA LTD. | 2.81% |
| HUM | HUMANA INC | 2.68% |
| NEO | NEOGENOMICS INC | 2.64% |
| AXSM | AXSOME THERAPEUTICS INC. | 2.51% |
| ALKS | ALKERMES INC | 2.51% |
| MRK | MERCK & CO. NEW | 2.45% |
| XENE | XENON PHARMACEUTICALS | 2.28% |
| BMY | BRISTOL MYERS SQUIBB CO | 2.14% |
| RVTY | REVVITY INC | 2.11% |
| THC | TENET HEALTHCARE CORP | 2.10% |
| BRKR | BRUKER CORP | 2.02% |
| ELV | ELEVANCE HEALTH INC | 1.95% |
| TSHA | TAYSHA GENE THERAPIES I | 1.92% |
| PCVX | VAXCYTE INC | 1.91% |
| DNLI | DENALI THERAPEUTICS INC. | 1.91% |
| IDYA | IDEAYA BIOSCIENCES, INC | 1.85% |
| UNH | UNITEDHEALTH GROUP INC | 1.77% |
| SNDX | SYNDAX PHARMACEUTICALS, INC. | 1.73% |
| RGEN | REPLIGEN CORP | 1.71% |
| WAT | WATERS CORP | 1.70% |
| AVTX | AVALO THERAPEUTICS INC | 1.69% |
| ABBV | ABBVIE INC | 1.69% |
| TMO | THERMO FISHER SCIENTIFIC INC | 1.68% |
| ICLR | ICON PLC | 1.67% |
| MCK | MCKESSON CORP | 1.62% |
| DYN | DYNE THERAPEUTICS, INC. | 1.53% |
| VCEL | VERICEL CORP | 1.53% |
| ARQT | ARCUTIS BIOTHERAPEUTICS | 1.51% |
| MDT | MEDTRONIC PLC | 1.51% |
| LLY | ELI LILLY CORP | 1.49% |
| TNDM | TANDEM DIABETES CARE INC | 1.45% |
| DHR | DANAHER CORP | 1.40% |
| AZN | ASTRAZENECA PLC | 1.39% |
| GEHC | GE HEALTHCARE TECHNOLOGIES INC | 1.39% |
| HCA | HCA HOLDINGS INC | 1.39% |
| PRQR | PROQR THERAPEUTICS NV | 1.36% |
| ALC | ALCON INC | 1.34% |
| SNY | SANOFI- AVENTIS- ADR | 1.29% |
| ABT | ABBOTT LABORATORIES | 1.25% |
| IRON | DISC MEDICINE INC | 1.23% |
| IONS | IONIS PHARMACEUTICALS INC | 1.20% |
| SYK | STRYKER CORP | 1.14% |
| ISRG | INTUITIVE SURGICAL INC | 1.02% |
| ZTS | ZOETIS INC | 0.97% |
| JANX | JANUX THERAPEUTICS INC | 0.92% |
| SPRY | ARS PHARMACEUTICALS | 0.92% |
| OCS | OCULIS HOLDING AG | 0.85% |
| FULC | FULCRUM THERAPEUTICS, INC. | 0.69% |
| RARE | ULTRAGENYX PHARMACEUTICAL INC | 0.68% |
| BSX | BOSTON SCIENTIFIC | 0.65% |
| PODD | INSULET CORP | 0.62% |
| EYPT | EYEPOINT INC | 0.58% |
Read a prospectus and summary prospectus (if available) carefully before investing. It contains the investment objective, risks charges, expenses and the other information, which should be considered carefully before investing. To obtain a prospectus and summary prospectus (if available) <a href="/services/prospectuses-and-reports">click here</a> or call 800.820.0888.
Investing involves risk, including the possible loss of principal.
Guggenheim Investments represents the following affiliated investment management businesses of Guggenheim Partners, LLC: Guggenheim Partners Investment Management, LLC, Security Investors, LLC, Guggenheim Funds Distributors, LLC, Guggenheim Funds Investment Advisors, LLC, Guggenheim Corporate Funding, LLC, Guggenheim Wealth Solutions, LLC, Guggenheim Private Investments, LLC, Guggenheim Investments Loan Advisors, LLC, Guggenheim Partners Europe Limited, Guggenheim Partners Japan Limited, and GS GAMMA Advisors, LLC. Securities offered through Guggenheim Funds Distributors, LLC.
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