| Symbol | Company | Weighting |
|---|---|---|
| RVMD | REVOLUTION MEDICINES INC | 4.45% |
| KRRO | KORRO BIO | 3.26% |
| ARWR | ARROWHEAD PHARMACEUTICALS INC | 3.13% |
| URGN | UROGEN PHARMA LTD. | 3.02% |
| EWTX | EDGEWISE THERAPEUTICS | 2.90% |
| TVTX | TRAVERE THERAPEUTICS INC | 2.69% |
| ALKS | ALKERMES INC | 2.52% |
| HUM | HUMANA INC | 2.40% |
| NEO | NEOGENOMICS INC | 2.29% |
| AXSM | AXSOME THERAPEUTICS INC. | 2.29% |
| XENE | XENON PHARMACEUTICALS | 2.28% |
| MRK | MERCK & CO. NEW | 2.18% |
| TSHA | TAYSHA GENE THERAPIES I | 2.15% |
| DNLI | DENALI THERAPEUTICS INC. | 2.08% |
| BRKR | BRUKER CORP | 2.06% |
| DYN | DYNE THERAPEUTICS, INC. | 2.03% |
| BMY | BRISTOL MYERS SQUIBB CO | 2.02% |
| THC | TENET HEALTHCARE CORP | 2.01% |
| AVTX | AVALO THERAPEUTICS INC | 1.94% |
| EYPT | EYEPOINT INC | 1.90% |
| RVTY | REVVITY INC | 1.87% |
| TNDM | TANDEM DIABETES CARE INC | 1.82% |
| SNDX | SYNDAX PHARMACEUTICALS, INC. | 1.78% |
| UNH | UNITEDHEALTH GROUP INC | 1.77% |
| ELV | ELEVANCE HEALTH INC | 1.76% |
| PCVX | VAXCYTE INC | 1.76% |
| IDYA | IDEAYA BIOSCIENCES, INC | 1.69% |
| VCEL | VERICEL CORP | 1.66% |
| RGEN | REPLIGEN CORP | 1.63% |
| WAT | WATERS CORP | 1.62% |
| ARQT | ARCUTIS BIOTHERAPEUTICS | 1.56% |
| ABBV | ABBVIE INC | 1.54% |
| TMO | THERMO FISHER SCIENTIFIC INC | 1.52% |
| ICLR | ICON PLC | 1.52% |
| MCK | MCKESSON CORP | 1.51% |
| GEHC | GE HEALTHCARE TECHNOLOGIES INC | 1.51% |
| LLY | ELI LILLY CORP | 1.50% |
| MDT | MEDTRONIC PLC | 1.42% |
| ALC | ALCON INC | 1.42% |
| DHR | DANAHER CORP | 1.34% |
| SYK | STRYKER CORP | 1.33% |
| PRQR | PROQR THERAPEUTICS NV | 1.32% |
| IRON | DISC MEDICINE INC | 1.30% |
| AZN | ASTRAZENECA PLC | 1.28% |
| ABT | ABBOTT LABORATORIES | 1.28% |
| SNY | SANOFI- AVENTIS- ADR | 1.25% |
| HCA | HCA HOLDINGS INC | 1.24% |
| IONS | IONIS PHARMACEUTICALS INC | 1.20% |
| RARE | ULTRAGENYX PHARMACEUTICAL INC | 1.19% |
| SPRY | ARS PHARMACEUTICALS | 1.03% |
| ISRG | INTUITIVE SURGICAL INC | 1.02% |
| OCS | OCULIS HOLDING AG | 0.98% |
| ZTS | ZOETIS INC | 0.92% |
| JANX | JANUX THERAPEUTICS INC | 0.82% |
| BSX | BOSTON SCIENTIFIC | 0.74% |
| FULC | FULCRUM THERAPEUTICS, INC. | 0.64% |
| PODD | INSULET CORP | 0.63% |
Read a prospectus and summary prospectus (if available) carefully before investing. It contains the investment objective, risks charges, expenses and the other information, which should be considered carefully before investing. To obtain a prospectus and summary prospectus (if available) <a href="/services/prospectuses-and-reports">click here</a> or call 800.820.0888.
Investing involves risk, including the possible loss of principal.
Guggenheim Investments represents the following affiliated investment management businesses of Guggenheim Partners, LLC: Guggenheim Partners Investment Management, LLC, Security Investors, LLC, Guggenheim Funds Distributors, LLC, Guggenheim Funds Investment Advisors, LLC, Guggenheim Corporate Funding, LLC, Guggenheim Wealth Solutions, LLC, Guggenheim Private Investments, LLC, Guggenheim Investments Loan Advisors, LLC, Guggenheim Partners Europe Limited, Guggenheim Partners Japan Limited, and GS GAMMA Advisors, LLC. Securities offered through Guggenheim Funds Distributors, LLC.
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