| Symbol | Company | Weighting |
|---|---|---|
| ABVX | ABIVAX SA | 21.25% |
| RVMD | REVOLUTION MEDICINES INC | 5.02% |
| TVTX | TRAVERE THERAPEUTICS INC | 3.56% |
| EWTX | EDGEWISE THERAPEUTICS | 2.86% |
| PSNL | PERSONALIS | 2.79% |
| IMVT | IMMUNOVANT INC | 2.69% |
| ADPT | ADAPTIVE BIOTECHNOLOGIES CORPORATION | 2.69% |
| CRNX | CRINETICS PHARMACEUTICALS INC | 2.62% |
| CYTK | CYTOKINETICS INC | 2.40% |
| EYPT | EYEPOINT INC | 2.21% |
| DYN | DYNE THERAPEUTICS, INC. | 2.16% |
| TEVA | TEVA PHARMACEUTICAL INDS LTD | 2.03% |
| HALO | HALOZYME THERAPEUTICS INC | 1.93% |
| INSM | INSMED INC | 1.86% |
| GKOS | GLAUKOS CORPORATION | 1.85% |
| PCVX | VAXCYTE INC | 1.76% |
| DNLI | DENALI THERAPEUTICS INC. | 1.75% |
| ASND | ASCENDIS PHARMA A/S DKK 1.0 ADR | 1.56% |
| THC | TENET HEALTHCARE CORP | 1.51% |
| HUM | HUMANA INC | 1.50% |
| TARS | TARSUS PHARMACEUTICALS | 1.44% |
| ARGX | ARGENX SE ADR | 1.40% |
| GMED | GLOBUS MEDICAL INC CLASS A | 1.30% |
| UNH | UNITEDHEALTH GROUP INC | 1.30% |
| RGEN | REPLIGEN CORP | 1.26% |
| ABBV | ABBVIE INC | 1.25% |
| ICLR | ICON PLC | 1.18% |
| TMO | THERMO FISHER SCIENTIFIC INC | 1.17% |
| MCK | MCKESSON CORP | 1.16% |
| AZN | ASTRAZENECA PLC | 1.15% |
| BMRN | BIOMARIN PHARAMCEUTICAL INC | 1.05% |
| REGN | REGENERON PHARMACEUTICALS | 1.05% |
| DHR | DANAHER CORP | 1.04% |
| HCA | HCA HOLDINGS INC | 1.03% |
| VCEL | VERICEL CORP | 1.02% |
| ELV | ELEVANCE HEALTH INC | 0.98% |
| MDT | MEDTRONIC PLC | 0.98% |
| BDX | BECTON DICKINSON & CO | 0.96% |
| DXCM | DEXCOM INC | 0.95% |
| GEHC | GE HEALTHCARE TECHNOLOGIES INC | 0.94% |
| TNDM | TANDEM DIABETES CARE INC | 0.94% |
| KRRO | KORRO BIO | 0.85% |
| SYK | STRYKER CORP | 0.84% |
| RMD | RESMED INC | 0.83% |
| SNY | SANOFI- AVENTIS- ADR | 0.81% |
| ALC | ALCON INC | 0.78% |
| ABT | ABBOTT LABORATORIES | 0.77% |
| RARE | ULTRAGENYX PHARMACEUTICAL INC | 0.70% |
| ISRG | INTUITIVE SURGICAL INC | 0.62% |
| CDXS | CODEXIS INC | 0.58% |
| SMMT | SUMMIT THERAPEUTICS INC. | 0.57% |
| ADMA | ADMA BIOLOGICS, INC. | 0.49% |
| SRPT | SAREPTA THERAPEUTICS INC | 0.45% |
| BSX | BOSTON SCIENTIFIC | 0.45% |
| SPRY | ARS PHARMACEUTICALS | 0.44% |
| ZTS | ZOETIS INC | 0.42% |
| INSP | INSPIRE MEDICAL SYSTEMS, INC. | 0.37% |
| WAT | WATERS CORP | 0.30% |
| LENZ | LENZ THERAPEUTICS | 0.19% |
| AKROCV | CONTRA AKERO THERAPEUT | 0.00% |
Read a prospectus and summary prospectus (if available) carefully before investing. It contains the investment objective, risks charges, expenses and the other information, which should be considered carefully before investing. To obtain a prospectus and summary prospectus (if available) <a href="/services/prospectuses-and-reports">click here</a> or call 800.820.0888.
Investing involves risk, including the possible loss of principal.
Guggenheim Investments represents the following affiliated investment management businesses of Guggenheim Partners, LLC: Guggenheim Partners Investment Management, LLC, Security Investors, LLC, Guggenheim Funds Distributors, LLC, Guggenheim Funds Investment Advisors, LLC, Guggenheim Corporate Funding, LLC, Guggenheim Wealth Solutions, LLC, Guggenheim Private Investments, LLC, Guggenheim Investments Loan Advisors, LLC, Guggenheim Partners Europe Limited, Guggenheim Partners Japan Limited, and GS GAMMA Advisors, LLC. Securities offered through Guggenheim Funds Distributors, LLC.
© 2026 Guggenheim Investments. All Rights Reserved.
Research our firm with FINRA Broker Check.
Not FDIC Insured • No Bank Guarantee • May Lose Value
This website is directed to and intended for use by citizens or residents of the United States of America only. The material provided on this website is not intended as a recommendation or as investment advice of any kind, including in connection with rollovers, transfers, and distributions. Such material is not provided in a fiduciary capacity, may not be relied upon for or in connection with the making of investment decisions, and does not constitute a solicitation of an offer to buy or sell securities. All content has been provided for informational or educational purposes only and is not intended to be and should not be construed as legal or tax advice and/or a legal opinion. Always consult a financial, tax and/or legal professional regarding your specific situation. Investing involves risk, including the possible loss of principal.